Anker 2.4G Vertical Ergonomic Mouse in a bright desk setup

A handshake grip for a sore wrist, for twenty-five dollars

Anker 2.4G Vertical Ergonomic Mouse

8.5/10medium confidenceLast checked
Er

Reviewed by

Eran Yorkovsky · Founder, PickGrade

Wrist relief without the gamble. The vertical handshake shape rotates your hand into a neutral angle, and reviewers say it eases pain as well as mice costing triple. It runs on AAAs and caps at 1600 DPI, but as a cheap first try at a vertical mouse, it's the easy call.

The cheapest sensible way to find out if a vertical mouse fixes your wrist. The whole point is the "handshake" shape, which rotates your hand and forearm into a neutral position instead of the palm-down twist of a normal mouse, and long-time users consistently report real relief, with reviewers rating it as comfortable as vertical mice that cost three times as much. For around $25 you still get a tactile coating, an onboard DPI selector, five buttons with back/forward, and a slot for the receiver. The compromises are the price: disposable AAA batteries with no rechargeable option, no Bluetooth (a single 2.4GHz dongle, so no tablets or device-hopping), a 1,600 DPI ceiling that rules out gaming, and a right-handed-only shape whose thumb buttons can stretch small hands. If your wrist needs a vertical grip and budget matters, start here.

$25

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Last reviewed Jun 11, 2026

AI grade·Refined by real owners

What we like

  • Affordable ergonomic option
  • Vertical wrist angle
  • Good starter shape

Trade-offs

  • Disposable AAA batteries (not included; no rechargeable option)
  • No Bluetooth - single 2.4GHz channel, no multi-device or tablet pairing
  • Sensor tops out at 1,600 DPI - not for gaming or high-res precision
  • Right-handed only; thumb buttons a stretch for small hands

Best for

Anyone with wrist discomfort who wants to try the vertical "handshake" grip cheaply before committing to a premium ergonomic mouse.

Avoid if

You need precision work, gaming performance, or rechargeable batteries — this is a basic AAA-powered starter mouse.

The three lenses

How we grade →

Score breakdown

  • value9.2/10
  • ease8.6/10
  • fit8.5/10
  • quality8.0/10

Specs

dpi
Onboard selector: 800 / 1,200 / 1,600
type
Budget vertical ergonomic mouse
power
2x AAA batteries (not included)
price
~$25
shape
Vertical handshake position (eases wrist strain)
extras
Tactile coating; dongle storage slot
buttons
5 (incl. back/forward navigation)
connectivity
2.4GHz USB dongle (no Bluetooth)

How we know

Medium confidenceLast checked

The Anker 2.4G Wireless Vertical Ergonomic Mouse is PickGrade's budget pick — and proof you don't need to spend much to ease wrist strain. Its whole point is the vertical 'handshake' shape, which rotates your hand and forearm into a neutral position rather than the palm-down twist of a normal mouse; reviewers and long-time users consistently report real relief from wrist and forearm pain, and Tom's Guide and Digital Camera World rate it as comfortable as vertical mice costing three times as much. For around $25 you still get a usable feature set: a tactile rubber coating, an onboard DPI selector (800/1,200/1,600), five buttons including back/forward navigation, and a slot to stash the USB receiver. It's plug-and-play over a 2.4GHz dongle. The honest caveats: it runs on disposable AAA batteries (not included, no rechargeable option); there's no Bluetooth and only a single 2.4GHz channel, so you can't pair it with tablets or hop between devices; the sensor tops out at a modest 1,600 DPI, fine for office work but not for gaming or high-resolution precision; it's right-handed only; and people with smaller hands can find the thumb buttons a stretch. If a vertical shape is what your wrist needs and budget matters, it's the easy first try.

Compare Anker 2.4G Vertical Ergonomic Mouse with the top alternates side-by-side.

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Video reviews

  • YouTubeAnker 2.4G Wireless Vertical Mouse - Honest Review

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